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37830

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3,4-Dihydroxy-L-phenylalanine

purum, ≥99.0% (NT)

Synonym:3-(3,4-Dihydroxyphenyl)-L-alanine, L-3-Hydroxytyrosine, L-DOPA, Levodopa
CAS Number:59-92-7
Linear Formula:(HO)2C6H3CH2CH(NH2)CO2H
Molecular Weight:197.19
Beilstein Registry Number:2215169
EC Number:200-445-2
MDL number:MFCD00002598
PubChem Substance ID:24863554

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Description

Other NotesSubstrate for the assay of tyrosinase (EC 1.14.18.1)1,2; aromatic L-amino acid decarboxylase EC 4.1.1.28)3; lactoperoxidase (EC 1.11.1.7)4

Properties

gradepurum
assay≥99.0% (NT)
optical activity[α]20/D −12±1°, c = 1% in 1 M HCl
mp276-278 °C(lit.)

Safety

Personal Protective Equipmentdust mask type N95 (US), Eyeshields, Gloves
Hazard CodesXn
Risk Statements22-36/37/38
Safety Statements26-36
WGK Germany3
RTECSAY5600000

References

Cited Reference1. J. Vachtenheim et al. Anal. Biochem. 146, 405, (1985) Abstract
 2. S.H. Pomeranntz, J.P.-C. Li Meth. Enzymol. 17A, 620, (1970)
 3. C. B. Voltattorini et al. Meth. Enzymol. 142, 179, (1987) Abstract
 4. D. Polis, H.W. Shmukler Meth. Enzymol. 2, 813, (1957)
referenceFeigin, A., Metabolic correlates of levodopa response in Parkinson's disease. Neurology 57, 2083, (2001)
MerckMerck 13,5485
BeilsteinBeil. 14,IV,2492
 FT-IR 2 (2), 2753:A / FT-IR 1 (2), 257:B / FT-NMR 1 (2), 1190:B / IR-Spectra (3), 999:A / IR-Spectra (2), 874:F / RegBook 1 (2), 1847:I / Sax 6, 1076 / Sigma FT-IR 1 (1), 139:B / Structure Index 1, 296:A:5